The Munson lab is committed to open access, transparency, and data availability. We are in the process of publishing our datasets and other research products to NIH.Figshare.com or Figshare.com under the open access Creative Commons Attribution License (CC BY). Under this copyright license users may distribute, remix, adapt, and build upon our data in any medium or format, provided attribution is given to the Munson lab by citation of the materials’ DOI and associated publications.
Data associated with publication “CexE is a Coat Protein and Virulence Factor of Diarrheagenic Pathogens” Zachary P. Rivas, Kacey M. Talbot, Leidy C. Merselis, Ryan M. McCormack, Rebecca Adkins, and George P. Munson. Frontiers in Microbiology 2020. doi: 10.3389/fmicb.2020.01374
Unpublished data demonstrating that perforin-2 (mpeg1) knockout mice are not more resistant to LPS induced septic shock than wild-type mice. Additional unpublished data from an RNAseq study suggesting Perforin-2 is not required for Type I Interferon signaling.
Data for figures 1 through 6 and replicate Western blots of “Perforin-2 Breaches the Envelope of Phagocytosed Bacteria Allowing Antimicrobial Effectors Access to Intracellular Targets,” Fangfang Bai, Ryan M. McCormack, Suzanne Hower, Gregory V. Plano, Mathias G. Lichtenheld and George P. Munson, J Immunol November 1, 2018, 201 (9) 2710-2720, https://doi.org/10.4049/jimmunol.1800365
Survival curves of wild-type and perforin-2 (mpeg1) deficient mice challenged with Yersinia pseudotuberculosis or an isogenic cif::aadA mutant. Data for Figures 8 and 9 of “Enteric Pathogens Deploy Cell Cycle Inhibiting Factors to Block the Bactericidal Activity of Perforin-2,” McCormack, Lyapichev,Olsson, Podack, and Munson. Elife. 2015 Sep 29;4:e06505. PMID: 26418746 PMCID: PMC4626573 https://doi.org/10.7554/eLife.06505.003
Collection of movies highlighting the structures of Perforin-2 pre-pores and pores. The collection includes structure rotations and animated flights through and around the murine Perforin-2 (MPEG1) polymers at various resolutions up to 1080p. Suitable for teaching and other educational activities. These movies were generated from the PDB structure files associated with “Structure and mechanism of bactericidal mammalian perforin-2, an ancient agent of innate immunity.” Ni, T., Jiao, F., Yu, X., Aden, S., Ginger, L., Williams, S. I., Bai, F., Pražák, V., Karia, D., Stansfeld, P., Zhang, P., Munson, G., Anderluh, G., Scheuring, S., & Gilbert, R. J. C. Science Advances. 2020, 6(5), eaax8286. https://doi.org/10.1126/sciadv.aax8286
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